Structure
Although nervous tissue is highly complex, it is made up of just two principal cell types: neurons and supporting cells, which
are also known as neuroglia or glial cells. There are six types of neuroglia, each with a specific structure and function.
Even though Schwann cells are derived from neural crest cells, they are still considered to be neuroglial cells. They are
flattened cells with only a few mitochondria and a small Golgi complex. Schwann cells are part of the peripheral nervous
system (PNS) that lies outside of the central nervous system (CNS).
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Function
Although nervous tissue is highly complex, it is made up of just two principal cell types: neurons and supporting cells, which
are also known as neuroglia or glial cells. There are six types of neuroglia, each with a specific structure and function.
Even though Schwann cells are derived from neural crest cells, they are still considered to be neuroglial cells. Schwann
cells perform the same role in the PNS as the oligodendrocytes do in the CNS. They also synthesise the insulating and protective
lipoprotein myelin, but they are capable of producing far less than the oligodendrocytes. This is reflected by the fact that
oligodendrocytes are able to myelinate several internodes of several neuronal axons in the CNS, whereas schwann cells can
only myelinate one internode of one axon in the PNS. Schwann cells are essential to the process of peripheral nerve fiber
regeneration.
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